Stimulate your body's own collagen production for gradual, natural-looking volume restoration and skin quality improvement that lasts 2+ years—the longest-lasting injectable option available.
What Are Biostimulators?
Biostimulators are a unique category of injectables that work differently than traditional dermal fillers. Instead of simply adding volume with gel, biostimulators trigger your body's natural collagen production process. The result? Gradual, natural-looking volume restoration and improved skin quality that develops over time and lasts significantly longer than traditional fillers.
Think of biostimulators as an investment in your skin's future. While traditional fillers give immediate results that fade in 6-12 months, biostimulators work with your body to build collagen gradually, with results that can last 2+ years.
At WishLane, we offer three biostimulator options: Sculptra, Radiesse, and Renuva. Each works uniquely to restore volume and improve skin quality over time.
Our Biostimulator Options
Sculptra
$800 per vial
Poly-L-lactic acid (PLLA) that gradually stimulates collagen production deep within the skin. Sculptra doesn't provide immediate volume—instead, it works over several months to restore facial fullness naturally. FDA-approved for treating facial fat loss and wrinkles.
Best for: Overall facial volume restoration, hollow cheeks, temples, nasolabial folds. Ideal for patients seeking subtle, natural-looking rejuvenation that develops over time.
Results: Gradual improvement over 2-3 months, lasting 2+ years. Typically requires 2-3 treatment sessions spaced 4-6 weeks apart.
Radiesse
$800 per syringe
Calcium hydroxylapatite (CaHA) microspheres suspended in a gel carrier. Radiesse provides immediate volume from the gel, plus long-term collagen stimulation from the CaHA particles. A hybrid approach—instant results that continue improving over time.
Best for: Cheeks, nasolabial folds, marionette lines, jawline contouring, hand rejuvenation. Great for patients who want both immediate and long-lasting results.
Results: Immediate volume plus gradual collagen building over 3-6 months. Results last 12-18+ months. Often requires just 1-2 treatment sessions.
Renuva
Starting at $1,200
Allograft adipose matrix—a processed human fat tissue that acts as a scaffold for your body to grow its own fat cells. Renuva is a truly regenerative approach to volume restoration. Your body replaces the matrix with your own living fat tissue over time.
Best for: Facial volume loss, body contouring, hand rejuvenation, areas where you want permanent fat grafting results without surgery. Unique alternative to traditional fillers.
Results: Gradual volume improvement as your body grows new fat cells (3-6 months). Results can be permanent with proper integration. May require 1-2 sessions depending on volume needed.
How to Choose?
Each biostimulator has unique benefits. Here's how we help you decide:
Choose Sculptra if you want:
- The most subtle, gradual, natural-looking results
- Overall facial rejuvenation and volume restoration
- The longest-lasting collagen stimulation (2+ years)
- To avoid any "just got filler" look
Choose Radiesse if you want:
- Immediate volume plus long-term collagen building
- Hand rejuvenation or jawline contouring
- Both instant gratification and lasting results
- Fewer treatment sessions (often just 1-2)
Choose Renuva if you want:
- The most regenerative, "permanent" approach
- To replace lost fat with your own living fat tissue
- Results that integrate naturally with your body
- An alternative to surgical fat grafting
Biostimulators vs. Traditional Fillers
Understanding the difference helps you choose the right treatment:
Traditional Fillers (HA-based)
- Add immediate volume with gel
- Results visible right away
- Last 6-18 months
- Reversible with hyaluronidase
- Great for lips, under-eye hollows, specific lines
Biostimulators
- Stimulate your own collagen/fat production
- Results develop gradually (weeks to months)
- Last 12-24+ months (or permanent with Renuva)
- Not reversible (except Radiesse has some immediate volume)
- Great for overall volume restoration, facial rejuvenation, skin quality improvement
Many patients benefit from both! We often use traditional fillers for specific areas like lips or tear troughs, and biostimulators for overall facial volume restoration and long-term collagen building.
What to Expect
During Treatment
Treatment takes 30-45 minutes. We apply topical numbing cream beforehand for comfort. Injection technique varies by product—Sculptra is often injected more deeply and requires post-treatment massage, while Radiesse and Renuva are placed more superficially.
After Treatment
Sculptra: You'll need to massage treated areas for 5 minutes, 5 times per day, for 5 days ("rule of 5s") to ensure even product distribution. Some initial fullness from the water-based gel that goes away in 2-3 days.
Radiesse: Immediate volume visible. Minimal massage needed. Avoid strenuous activity for 24-48 hours.
Renuva: Some initial swelling and firmness. Results develop gradually as your body regenerates fat tissue.
Common for all: Swelling, bruising, and tenderness at injection sites. These resolve within 3-7 days.
Results Timeline
Sculptra: Gradual improvement over 2-3 months as collagen builds. Peak results at 3-6 months. Lasts 2+ years.
Radiesse: Immediate volume from gel. Continued improvement over 3-6 months as collagen develops. Lasts 12-18+ months.
Renuva: Gradual volume as your body grows fat cells (3-6 months). Results can be permanent with successful integration.
Frequently Asked Questions
How many treatments will I need?
Sculptra: Typically 2-3 sessions spaced 4-6 weeks apart for optimal collagen building.
Radiesse: Often 1-2 sessions depending on volume needed.
Renuva: Usually 1-2 sessions depending on the area and desired volume.
Are biostimulators reversible?
No. Unlike HA fillers (which can be dissolved), biostimulators work by stimulating your body's own collagen or fat production. Results cannot be reversed. This is why we start conservatively and build gradually.
Will results look natural?
Yes! Biostimulators create some of the most natural-looking results because they work with your body's own collagen/fat. Results develop gradually, so there's no sudden change. You just look refreshed and rejuvenated—like a better version of yourself.
Are biostimulators safe?
Yes. All three products are FDA-approved and have excellent safety profiles when administered by trained professionals. Sculptra and Radiesse have been used safely for decades. Renuva uses processed human tissue that's been thoroughly screened and sterilized.
Can I combine biostimulators with other treatments?
Absolutely! Biostimulators work beautifully alongside neuromodulators (Botox, Dysport), traditional fillers, lasers, and other treatments. We often create comprehensive treatment plans that combine multiple modalities for optimal results.
Which biostimulator is best for me?
It depends on your goals, timeline, budget, and treatment areas. During your consultation, we'll assess your facial anatomy, discuss your aesthetic goals, and recommend the best option. Many patients love Sculptra for overall facial rejuvenation, Radiesse for immediate + long-term results, and Renuva for truly regenerative, permanent volume restoration.
Ready to Invest in Long-Lasting Results?
Schedule a consultation and we'll create a personalized biostimulator treatment plan to help you achieve natural, lasting rejuvenation.
Book Your ConsultationQuestions? Call or text us at 920-512-8822
